Skip to content

Multi-Component State Model Visualisation

Multi-Component State Model Visualisation
Open the Demo

This component is concerned with the visualisation of a multi-component state model coupled (biological) system. Each component can be modelled through its own individual state model, including dependencies on the environment such as ion concentrations, voltages or other variables.

Electrophysiological Cancer Cell Model

PyPI - Version

Attempt to model an A549 cancer cell's ion channels using an HMM (Hidden Markov Model) and simulation of voltage + current development accross the membrane of the cell.

This software comes in three flavours:

  • to run the main.rs simulation, do cargo run,
  • to compile the Python module, do maturin develop --features pyo3,
  • to precompile for the Astro dashboard, do bun run wasm-pack build frontend.

A visual to capture your interest:

Ion Channels (Image source: here).

This computational model is based on Langthaler et al., 2021: A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma.

The Simulation Dashboard

Screenshot of the User Interface